Doctors’ Outlook on Management of Multiple Sclerosis: Survey Report
Multiple Sclerosis (MS) is one of the most common inflammatory neurological diseases affecting young adults. Various emerging therapies aim to reduce the global MS burden. However, physicians face many challenges while developing a management strategy for MS patients. Data from recent publications and case reports reveal many misdiagnosed cases of MS. Evaluating different treatments and identifying the most effective method is crucial but difficult.
We conducted a survey to acquire physicians’ insights pertaining to this and other hurdles related to the management of MS.
Aim: To gauge doctors’ outlook on managing MS
Methodology: A nationwide online poll on Docplexus
Sample Size: 1,704 doctors comprising Neurologists, Neurosurgeons, General Physicians and Consulting Physicians.
The fundamental pathological data for MS was revealed by histopathological studies in 1838 by Carswell and in 1941 by Cruveilhier. It is characterized by an array of lesions such as focal demyelination, gliosis, inflammation and consequent axonal damage. Thus, the symptoms of MS may overlap with other neurological disorders. Owing to the complex presentation of the disease, the diagnosis of MS poses great difficulty.
According to our survey, 92% of the doctors claim to have come across patients who were wrongly diagnosed with MS. Of this 34% of doctors reported that more than 50% of patients had a misdiagnosis of MS.
The timely and appropriate diagnosis of MS is hampered not only by the disease presentation but also due to the lack of adequate diagnostic tools. In our survey, 80% of physicians have enlisted the hurdles faced in diagnosis as – late and incorrect diagnosis and the dearth of a sensitive diagnostic method.
Principles of Management
Upon confirmation of the diagnosis, management of MS consists of various multidisciplinary approaches; pharmacological as well as non-pharmacological strategies. Treating active MS is often further complicated by versatile therapeutic regimens or switching between the classes of drugs.
76% of doctors agree that treatment plan for MS patients should focus on all of the following aspects
• Delaying the disease progression
• Focusing on physical rehabilitation
• Setting patient defined goals of the treatment
Therapies preferred by clinicians
While 42% of the clinicians show an inclination towards disease-modifying medications, 25% believe in combination therapy. Some of the preferred combinations stated by the clinicians are,
• Steroids in acute attack, followed by disease-modifying agents
• Steroids, disease-modifying agents and traditional immunosuppressants
• Steroids and immunosuppressants
Obstacles in dealing with MS
Despite the advances in therapies for treating MS, the management practices fall short of obtaining ideal outcomes. Discussing the causes for this insufficiency, 45% of the doctors believe that delay in the initiation of treatment is a major drawback. While 24% of the physicians believe that lack of patient awareness and education can give a setback to the treatment, other 22% also mention that the treatment may fail if cognitive symptoms like anxiety, depression and fatigue are overlooked.
Limitations of existing therapies
With the use of various classes of drugs, the treatment plan of MS may become elaborate. The current therapies are associated with many drawbacks in practice. 47% of doctors believe that there is a lack of evidence for treatment of progressive MS. While 30% of the doctors mention high cost of the available drugs to be a problem, 17% of doctors believe that unknown long-term efficacy could limit the use of current drugs.
Adapting the therapeutic regimen to the dynamic stages of MS is a major challenge faced by 43% of the doctors. 28% of doctors report that MS clinics are poorly equipped, while 24% claim that adherence to MS treatment is often poor.
What Can Pharma Do?
The above analysis brings forth the prevailing gaps in the management of MS, which marketers should address. The rising burden of MS necessitates more aggressive medications that allow stronger control over the symptoms of MS such as anxiety, depression and fatigue. Initiatives such as patient support programs could help improve overall awareness, affordability and adherence. Quick initial treatment can harness better clinical outcomes in MS patients. Therefore, marketers should prioritize physician awareness & education that will lead to timely detection and appropriate action.
Docplexus is the largest digital network of doctors in India & a trusted marketing partner of pharma & medical device companies. It empowers the industry partners to meaningfully engage with the medical community through data-driven, evidence-based marketing & brand management solutions such as Infocenters, Mindset Analysis, KOL Webinars, Sponsored Medical Updates, Online CMEs & more.